Chordoma: tumors within the spine or the base of the skull

Chordoma is a rare, slow-growing cancer arising from the notochord remnants. This structure is present during embryonic development and usually disappears before birth. It can occur anywhere along the spine, from the base of the skull to the tailbone, and may also occur in the sacrum or base of the skull. Chordomas account for about 1-2% of all primary bone tumors.

What are the symptoms of chordoma?

Common symptoms include: -Persistent pain or discomfort in the back, neck, or base of the skull -Headaches, especially those that become worse with activity -Weakness or numbness in the arms and legs -Vision or hearing loss -Difficulty swallowing or speaking -Balance problems -Weakness or numbness in the face -Loss of bladder or bowel control -Trouble breathing.

How is it diagnosed?  

Chordoma is typically diagnosed with a combination of imaging tests and biopsies. Imaging tests such as CT scans and MRI scans can help identify a chordoma’s location, size, and shape. A physical exam may also assess the patient’s symptoms. A biopsy, in which a sample of the tumor is removed and examined under a microscope, is usually needed to confirm a diagnosis of chordoma.

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How is chordoma treated?  

Chordoma is typically treated with a combination of therapies, including surgery, radiation therapy, and chemotherapy. Surgery is generally the primary treatment to remove as much of the tumor as possible. Radiation therapy may be used before or after surgery to destroy any remaining cancer cells. Chemotherapy may also be used to try to slow the growth of the tumor. In some cases, a clinical trial may be an option for treatment.

How serious is chordoma?

Chordoma is a rare but serious type of cancer that starts in the bones of the skull and spine. Although chordoma is considered rare, it is a serious form of cancer that can be difficult to treat and potentially life-threatening. Treatment often involves surgery and radiation therapy.

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